DoNotAge – Pure Apigenin 250 mg – 30, 60 & 366 Vegetable Caps

Pure Apigenin is a premium, scientifically-formulated flavonoid supplement designed to support healthy ageing, cellular energy, and neurological resilience. Apigenin is a naturally occurring plant compound that has been extensively studied for its ability to regulate CD38 activity, an enzyme involved in the degradation of NAD⁺. By inhibiting CD38, apigenin helps support optimal NAD⁺ levels, which are essential for cellular energy production, metabolic health, and longevity-related pathways.

Research suggests that apigenin alone may significantly increase NAD⁺ levels without the need for direct NAD⁺ precursors. Through this mechanism, apigenin supports sirtuin activation, cellular repair processes, and metabolic balance. In addition, apigenin has demonstrated antioxidant, anti-inflammatory, neuroprotective, and cardiovascular-supportive properties, making it a valuable addition to a longevity-focused wellness routine.

Key Benefits of Pure Apigenin

• Supports healthy NAD⁺ levels by inhibiting CD38 activity.
• Promotes healthy ageing through cellular energy and sirtuin activation.
• Provides neuroprotective support and helps maintain cognitive health.
• Exhibits antioxidant properties that help protect cells from oxidative stress.
• Supports anti-inflammatory pathways associated with long-term wellness.
• Contributes to cardiovascular health and metabolic balance.
• Supports cellular resilience and overall vitality.

How Pure Apigenin Works

Pure Apigenin works primarily by inhibiting CD38, an enzyme responsible for breaking down NAD⁺ in the body. By reducing CD38 activity, apigenin helps maintain higher intracellular NAD⁺ levels, which are critical for mitochondrial function, energy metabolism, and DNA repair processes.

Increased NAD⁺ availability supports the activation of sirtuins, a family of proteins involved in cellular maintenance, metabolic regulation, and healthy ageing. Through these pathways, apigenin may help protect against age-related metabolic stress and support long-term cellular health.

Apigenin has also been studied for its anti-inflammatory and neuroprotective effects. It may help modulate inflammatory cytokines, protect neurons from oxidative damage, and support cognitive function, with potential relevance for brain and nervous system health.

Ingredients & Purity

Active Ingredient: Apigenin – 250 mg per capsule

Inactive Ingredients: Vegetable cellulose capsule

Pure Apigenin is bound to beta glycosides for enhanced stability and long-term potency. The formula contains no fillers, additives, or artificial excipients.

Directions for Use

Take one capsule daily, preferably with a source of fat, at any time of the day. Pure Apigenin can be combined with other longevity-focused supplements such as NMN, Vitamin D3 & K2, Magnesium, or SIRT6 activators as part of a comprehensive wellness routine.

Quality & Testing

• Third-party tested for purity and quality
• Each batch tested to ensure purity above 99%
• Fully stabilised to preserve potency over time
• Contains no fillers, binders, or unnecessary excipients
• Vegetable capsules suitable for daily use

FAQ